In the kitchen cutscene of a zombie approaching a door, it's gray, but on the other side, it's brown.

During the cutscene showing a hunter running through the courtyard, the first metal door is missing, along with part of the wall around the corner.

In the Jill game-play, when Barry drops a rope for Jill to climb down, after she climbs down, the rope falls and completely disappears. However, there's no hole or trap door in the floor for the rope to disappear. The rope literally went through the floor and the game went on as if it really did go through the floor.

Towards the end of the game (if played correctly), the warning announcement on the PA says: "Unlock all routes for evacuation," but because of the triggering system being activated the entrance elevator is stalled. Also there are a few doors that are still locked under the triggering system.

In the underground Arklay Lab, there are a few rooms where there's a red light that would light up under an emergency. Once the triggering system is activated (an emergency situation), those red warning lights never lit up.

When you fight the Yawn snake in the attic, if you shoot it, or ignore it, there are no bullet wounds, but later on, when you return to the mansion, and fight the snake again, its head has several bullet wounds.

Towards the end of the game, your playable character reaches the B-4 level where Wesker is waiting for your arrival, but strangely the only elevator entry was out of power. So Wesker shouldn't be able to reach the B-4 level before you did if the power to the elevator was turned off.

There's a cutscene involving Barry and Jill in the main hall.  Barry hands Jill some acid rounds, but he doesn't have the bazooka it goes with in the first place.

In the beginning of Jill's scenario, Barry gives Jill a lock pick, claiming her to be an expert in using one. However, it is described in the game manual that Barry is an ex-SWAT team member, who are trained to use lock picks in various properties.

Trivia (IMDb)

The Director's Cut non-duel shock version came with the bonus game demo of Resident Evil 2.

Significant work on a port to Game Boy Color was completed before Capcom pulled the plug citing quality concerns. This port was a fairly direct adaptation of the original with characters moving about in 3D on prerendered backdrops.

When originally released in the US and Europe (for the PlayStation), the game had several cuts in its cutscenes, and some death sequences. Thankfully the PC version (excluding the UK version) restores all the missing stuff and plays like the original Japanese release.

Bravo Team's pilot, Dewey, was originally conceived as a thin African-American member of STARS who would've also served as the game's comic relief. He and another character named Gelzer were planned to appear in the game, but were discarded from the final version. The Edward Dewey in Biohazard 0 is a tall Caucasian and is a departure from the character's initial concept.

The Japanese version had a color intro but in the Western release the intro was Black & White and was censored.

This is and the remake versions are the only Resident Evil games with a best-case scenario in which when the mansion blew up, the story would be all over and the case solved.  This was just in case if the game failed, Capcom wouldn't plan on any further Resident Evil sequels.

Resident Evil was inspired by the Famicom (NES) Japanese game Sweet Home.

The movie Night Of The Living Dead is also an inspiration to create a game involving zombies.

The game was originally going to be called Biohazard worldwide (it is in Japan), but due to copyright issues, the name was changed to Resident Evil in other parts of the world.

The Sega Saturn version in Japan has an uncensored colored intro including Joseph's death extended and the Cerberus being torn apart by gunfire.

As of 2020, the game, in all versions, sold over 100 million copies worldwide.

It is never mentioned where in the US the fictional Raccoon City and the nearby Arklay Mountains are located, apart from that it is a Midwestern town. However, in the novels based on the games written by S.D. Perry, it is said to be located in Pennsylvania.

Chris Redfield's story continues in Resident Evil 2 (a diary telling his sister about his whereabouts), Resident Evil Code Veronica, Resident Evil 5, & Resident Evil 6. Jill's story continues in Resident Evil 3, Resident Evil Revelations, & Resident Evil 5.

This game has seen the most releases out of all the Resident Evil games (not even counting the remakes and their HD versions). These include the original PlayStation 1 version, the Sega Saturn port, the PC port, the Director's Cut for PlayStation, the Dual Shock version for PlayStation, the Nintendo DS remake and the unreleased Gameboy Color version.

This is the first video game to use the term "survival horror" even though past games had that genre already.

There were big differences between the original and Director's Cut versions of the game.  One is, the ability to choose what difficulty you want the game to be (standard, training, advance).  Another is in the advance mode, the characters have different outfits, different camera angles in some of the rooms and hallways, and items are in different locations, and the Beretta handgun has the ability to shoot headshots.  Lastly, the game comes with a playable demo disc of Resident Evil 2.

In 2022, Charlie Kraslavsky, Greg Smith and Eric Pirius, who had played Chris, Barry and Wesker respectively in the games live action cutscene, reunited in a number of YouTube videos where they were interviewed, seen playing the game and reprised their roles for the first time since 1995.

Also in 2024 they were reunited with again but this time joined by Linda on the set of the fan film The Keeper's Diary: A Biohazard Story (2024) Where they were interviewed again with Linda and she played the game for first time.

Capcom thought the game would only sell about 200,000 copies to a small niche of gamers, but ended up being a major hit that sold millions.

The game was made significantly more difficult for the American market, removing the auto-aim function and limiting the number of ink ribbons for saving. Preview copies also disabled the interconnected item boxes, but this feature was later restored in the final version. Increasing the game's difficulty was done at the request of Capcom USA to combat revenue lost from the rental market; this was relatively common practice at the time, reasoning that if a game was too difficult for players to finish during the rental period, they would be more inclined to eventually buy and complete it. Shinji Mikami admitted that this harder version of the game was even difficult for Capcom staff. The GameCube remake Resident Evil (2002) would later feature an unlockable mode where the item boxes were no longer connected.

Kenichi Iwao and Yasuyuki Saga wrote a lot of the in-game files that provide backstory to the game. One of the files that Saga wrote was called 'Trevor Memoirs', which detailed the fate of George Trevor, the mansion's original architect, his wife Jessica and daughter Lisa, who were all captured by Umbrella to prevent the company's secret research from being revealed to the world. The file also introduced the character of Oswell E. Spencer, the mansion's owner and co-founder of Umbrella. The file remained in the game until almost the last moment, when Saga asked director Shinji Mikami for its removal because he felt that Trevor's account was no longer consistent with other in-game files; Mikami agreed, but primarily because he feared that the file would reveal too much of the game's plot. The file and subplot were eventually re-written as 'Trevor's Diary', and used in the remake Resident Evil (2002) six years later, together with one of Iwao's unused ideas for a graveyard.

Resident Evil Directors Cut and the Japanese version Biohazard is included on the PlayStation Classic Mini console bundled with 20 games.

About the time Sony PlayStation came around, Resident Evil was originally planned for the Super Nintendo game console.  Since 1994, gaming graphics were starting to become more 3D and Capcom felt that the game would be better in 3D than in Nintendo's 16-bit version.  Resident Evil would eventually make it to a Nintendo game port in 2002 with the remake on the GameCube.

Pablo Kuntz, who voiced Albert Wesker, and his son, streamed them playing the game series online in 2023.

In some form (verbally, or written text in-game files), Albert Wesker is the only Resident Evil character who appears or is mentioned in every main Resident Evil games except for the spin-offs, as he is pretty much the catalyst for the whole series. In Resident Evil 0, he appears in certain cutscenes. In Resident Evil 2 & 3 the player can find his desk in the S.T.A.R.S' office. If examined, the player will say that it belongs to Wesker, leader of the S.T.A.R.S unit. In Resident Evil: Code Veronica, he plays a vital role in the storyline, appearing in certain key moments. In Resident Evil 4, he is mentioned by Ada Wong and seen on a small monitor. In Resident Evil 5, he is the main antagonist, and in Resident Evil 6, he is mentioned by Chris Redfield while talking to Jake, Wesker's son.

Barry Burton's part in the series will continue in Resident Evil 3: Nemesis (he saves Jill and Carlos in the good ending via helicopter in time for a missile to destroy Raccoon City).  He also continues in Revelations 2 as a playable character, and is playable in Resident Evil 5's mini game The Mercenaries Reunion.

The game's canonical ending is unachievable because regardless to which character you play as, in the best possible ending, one of the characters that appears in the other character's scenario isn't present in the helicopter when Chris, Jill for sure are saved, but Barry and Rebecca aren't in the final ending of the opposite play character.  For example: Rebecca couldn't be in the Jill Valentine ending, and Barry couldn't be in the Chris Redfield ending.